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• Chapter 1 : Fluid and Electrolyte Physiology

  • Distribution of Body Water, 1

  • Control of Body water, 3

  • Measurement of Compartment Volumes,

  • Control of Intracellular Volume,

  • Osmotic pressure,

  • Osmolality and Tonicity,

  • Oncotic pressure,

  • Sodium concentrations

  • Potassium

  • Functions of Magnesium,

  • Gibbs-Donnan Relationship,

  • Lymph,

  • Sweat,

  • Infusion of 1000mls of 3N Saline

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• Chapter 2: Acid-Base Physiology

  • Buffers

  • Respiratory Regulation of Acid-Base Balance

  • Renal Regulation of Acid-Base Balance

  • Effects of Hypercapnia,

  • Adverse Effects of Hypocapnia,

  • Interpretation of Arterial Blood Gases,

  • Infusion of 1N Hydrochloric Acid

  • Infusion of 8.4% Sodium Bicarbonate

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• Chapter 3: Cardiovascular Physiology

  • Ventricular Pressure Curve

  • Pressure-Volume Loop

  • Determinants of Myocardial Performance

  • Cardiac Output

  • Myocardial Oxygen Consumption

  • Valsalva Manoeuvre

  • CVS Response to Standing

  • CVS Response to Rapid Loss of 1000mls of Blood

  • Rapid Transfusion of 1000mls of IV Fluids

  • Cerebral Blood Flow,

  • Coronary Blood Flow

  • Hepatic Blood Flow

  • Renal Blood Flow

  • Microcirculation

  • Pulmonary Microcirculation

  • Autoregulation

  • Myocardial Action Potentials

  • Properties of Cardiac Muscle

  • Mixed Venous Blood

  • Distribution of Blood Volum

  • Effects of Anaemia

  • Venous Return,

  • Physiology of CPR,

  • Arterial Pulse Contours,

  • Cardiac and Vascular Function Curves,

  • Hyperventilation with Chest Compression

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• Chapter 4: Respiratory Physiology

  • Dead Space,

  • Lung Volumes

  • Functional Residual Capacity

  • Compliance

  • Closing Capacity

  • Oxygen Cascade

  • Oxygen Transport

  • Oxygen Dissociation Curve

  • Carbon Dioxide Transport

  • Differences between the Base and Apex of the Lung

  • Volume, Pressure & Flow during Normal Breathing

  • Physiology of Preoxygenation

  • Breathing 100% Oxygen

  • Resorption of a Pneumothorax

  • Cyanosis

  • Flow-Volume Loop

  • Surfactant

  • Non-Respiratory Functions of the Lung

  • Respiratory Response to High Altitude

  • Functions of the Nose

  • Functions of the Red Blood Cell

  • Mechanics of Breathing

  • Alveolar-arterial pO2 gradient

  • Hypoxaemia and Hypoxia

  • Shunt

  • Pulmonary Vascular Resistance

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• Chapter 5: Renal Physiology

  • Formation of Urine

  • Glomerular Filtration Rate

  • Preoperative Tests of Renal Function

  • Juxtaglomerular Apparatus,

  • Excretion of Bicarbonate by the Kidney

  • Renal Clearance,

  • Endocrine Functions of the Kidney

  • Excretion of Urea

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• Chapter 6: Endocrine Physiology and Metabolism

  • Hormones

  • Insulin

  • Regulation of the Blood Glucose Level

  • Synthesis of the Thyroid Hormones

  • The Pituitary

  • Control of Calcium Level

  • Mechanisms by which Hormones Interact with Cells

  • Metabolic Rate

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• Chapter 7: Physiology of Blood

  • Storage of Blood

  • Compatibility Testing of Blood

  • Plasma Proteins

  • The Immune System

  • Haemostasis

  • Iron Metabolism

  • Blood Groups

  • Complement

  • Vitamin K

  • Erythropoietin

  • Platelets

  • The Death of a Red Cell

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• Chapter 8: Gastrointestinal Physiology

  • Gastric Acid Secretion

  • Bile Acids

  • Functions of the Liver

  • Vomiting

  • Digestion and Absorption of Carbohydrates

  • Abdominal Pressure

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• Chapter 9: Neurophysiology

  • Cerebrospinal Fluid

  • Blood-Brain Barrier

  • Propagation of an Action Potential

  • Occulocardiac Reflex

  • Peripheral Nerves

  • Functions of the Hypothalamus

  • Resting Membrane Potential

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• Chapter 10: Physiology of Muscle and the Neuromuscular Junction

  • Muscle Spindles

  • Physiology of Neuromuscular Transmission

  • Physiology of Muscle Contraction

  • Smooth Muscle

  • Types of Skeletal Muscle

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• Chapter 11: Maternal, Foetal and Neonatal Physiology

  • Cardiorespiratory Changes at Birth

  • Functions of the Placenta

  • Neonatal Temperature Regulation

  • Maternal Cardiorespiratory Changes during Pregnancy

  • Neonatal Respiratory Physiology

  • Placental Gas Exchange

  • The First Breath

  • Amniotic Fluid

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• Chapter 12: Clinical Measurement

  • Exponential Functions,

  • Invasive Pressure Measurement

  • Gauge Pressure & Pressure Gauges

  • Strain Gauges

  • Oscillometric BP Measurement

  • Oxygen Analysis

  • Carbon Dioxide Analysis

  • Volatile Agent Monitoring

  • Pressure Changes during Insertion of a Pulmonary Artery Catheter

  • Temperature Measurement

  • Measurement of Humidity

  • Measurement of the Oxygen Content of a Blood Sample

  • Physical Principles of Vaporisers

  • Rotameters

  • Gas Laws

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• Chapter 13: Miscellaneous Topics

  • Body Temperature Regulation

  • Functions of the Skin

  • Intraocular Pressure

  • Physiological Principles in the Care of a Tracheostomy

  • Physiology of Anaphylaxis

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• AppendixA: Physiology Quick Quiz Questions

• Appendix B: Answers

• Abbreviations

• Index